American Association of Critical-Care Nurses (AACN) Certification Practice Test

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Cullen's sign is primarily associated with which condition?

  1. Gallbladder disease

  2. Pneumonia

  3. Pancreatitis

  4. Cholangitis

The correct answer is: Pancreatitis

Cullen's sign is primarily associated with pancreatitis. This clinical sign appears as a bluish discoloration around the umbilicus, which can result from the accumulation of blood in the abdominal cavity or peritoneal area, indicative of hemorrhagic conditions. In the case of pancreatitis, particularly when there is necrotizing pancreatitis or severe inflammation, the inflammation can lead to bleeding and subsequent bruising around the peritoneum. It's important to note that while Cullen's sign may be observed in other conditions as well, such as ectopic pregnancy or abdominal trauma, its association with pancreatitis is particularly noteworthy due to the underlying mechanisms of the disease. The presence of Cullen's sign in a patient with suspected pancreatitis can serve as a clinical clue for healthcare professionals, making it a significant finding in the diagnostic process.