American Association of Critical-Care Nurses (AACN) Certification Practice Test

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In Neuroleptic Malignant Syndrome, what is the threshold fever typically observed?

98-100°F
100-102°F
102-104°F
104-106°F

The correct answer is: 102-104°F

In Neuroleptic Malignant Syndrome (NMS), a significant and potentially life-threatening reaction to antipsychotic medications, the threshold fever that is typically observed is in the range of 102-104°F. This elevated temperature is one of the hallmark signs of NMS and indicates the dysregulation of the body's thermoregulatory system, which can occur as a result of the effects of neuroleptic medications on the central nervous system. The high fever associated with NMS is often accompanied by other symptoms such as muscle rigidity, altered mental status, and autonomic instability, making it critical to recognize and address this syndrome promptly. Maintaining awareness of the typical fever range helps healthcare professionals in the early identification of NMS and, consequently, in initiating appropriate treatment to manage this serious condition effectively.