American Association of Critical-Care Nurses (AACN) Certification Practice Test

What triad of symptoms is associated with cholangitis?

1. Fever, jaundice, and abdominal pain

2. Charcot's triad

3. Murphy's sign, fever, and leukocytosis

4. Reynold's pentad

The correct answer is: Charcot's triad

Cholangitis is an infection of the bile duct system, typically associated with a combination of symptoms that reflect the underlying process. The correct answer, "Charcot's triad," refers specifically to the classic presentation of cholangitis, which includes fever, jaundice, and right upper quadrant abdominal pain. Fever signifies the infectious aspect of the condition, indicating that the body is fighting off an infection. Jaundice occurs due to the obstruction of the bile ducts, leading to the accumulation of bilirubin in the bloodstream. Abdominal pain, particularly in the right upper quadrant, is commonly associated with inflammation or irritation of the liver or gallbladder, which can be exacerbated in cholangitis due to the infection and resulting swelling of the bile ducts. While other choices encompass symptoms or signs observed in different contexts, such as Murphy's sign (indicative of cholecystitis) or Reynold's pentad (which includes the triad of Charcot plus hypotension and mental status changes, indicating severe cholangitis), the triad itself specifically identifies the core symptoms characterizing cholangitis. Understanding Charcot's triad is fundamental for healthcare professionals, as it is critical for diagnosis and guiding appropriate treatment for patients suspected of