American Association of Critical-Care Nurses (AACN) Certification Practice Test

Which complication is most commonly associated with parenteral nutrition (PPN/TPN)?

1. Clogging

2. Dumping syndrome

3. Dehydration

4. Sepsis

The correct answer is: Clogging

The most commonly associated complication with parenteral nutrition, particularly partial parenteral nutrition (PPN) or total parenteral nutrition (TPN), is sepsis. This is due to the fact that the intravenous administration of nutrients creates an opportunity for bacteria to enter the bloodstream, especially if there is contamination of the catheter used for delivery or if sterile techniques are not strictly followed. Patients receiving such nutrition are typically immunocompromised or critically ill, making them more susceptible to infections. Frequent monitoring and maintaining strict aseptic technique during infusion can help mitigate this risk, but sepsis remains a significant concern in clinical settings. While clogging may occur due to precipitates forming in the TPN solution or issues with the catheter, it is generally not considered a direct complication of the nutrition itself and is less common than the risk of sepsis. Dumping syndrome is primarily associated with enteral feeding rather than parenteral nutrition. Dehydration can occur but is usually manageable with proper fluid administration, making sepsis the key concern.