American Association of Critical-Care Nurses (AACN) Certification Practice Test

Which medication class inhibits the conversion of angiotensin I to angiotensin II?

1. Calcium Channel Blockers

2. Beta Blockers

3. ACE Inhibitors

4. Diuretics

The correct answer is: ACE Inhibitors

The correct answer is ACE Inhibitors, which stands for Angiotensin-Converting Enzyme Inhibitors. This medication class specifically targets the enzymatic process that converts angiotensin I, which is relatively inactive, into angiotensin II, a potent vasoconstrictor that plays a critical role in regulating blood pressure and fluid balance in the body. By inhibiting this conversion, ACE Inhibitors effectively lower levels of angiotensin II, leading to vasodilation, decreased blood pressure, and reduced strain on the heart. In addition to their role in blood pressure management, ACE Inhibitors have benefits in heart failure and chronic kidney disease, as they help to reduce the workload on the heart and can protect kidney function over time. This mechanism of action is central to their therapeutic use in various cardiovascular and renal conditions. The other medication classes listed do not primarily focus on this specific mechanism of action. Calcium Channel Blockers work by preventing calcium from entering the cells of the heart and blood vessels, leading to relaxation of these muscles. Beta Blockers mainly affect the heart by blocking the action of adrenaline, thereby slowing the heart rate and reducing blood pressure. Diuretics function to promote the excretion of sodium and water,